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What is the term for the body's adaptation to a substance that leads to decreased responsiveness?

Craving

Tolerance

The term that describes the body's adaptation to a substance, which results in decreased responsiveness to its effects, is tolerance. Tolerance occurs when an individual needs to consume more of a substance to achieve the same effect that was initially experienced with a lower dose. This phenomenon can happen with various substances, including medications and recreational drugs, as the body becomes accustomed to their presence and adjusts its physiological responses accordingly. As a result, the user may find that what once produced a significant effect now requires a higher amount to elicit a similar response. Understanding tolerance is crucial in substance use and its potential risks, as it often leads to increased consumption and can contribute to other issues like dependence or addiction.

Addiction

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